Coffee Enema plays an important role in the detoxification of the body. The coffee enters the liver via the colon. This causes two effects: the dilation of the bile duct which enables the draining of the toxins from the liver, and the increase of the production of G.S.T (Glutathione S-Transferase) by 600% to 700%. The G.S.T. is an enzyme which helps to remove free radicals and other toxins from the blood.